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Spotting the Happy Early Signs of a Strong Clone

In cell line development (CLD), selection of the optimum clone within initial time frames is sought, so that costly resources can be focused from the earliest stage of a long process, on the optimal clone.

Here are details of integrating automated imaging, single-cell isolation, and early productivity assessment, into a unified, high-throughput workflow. The high-throughput screening, identification and transfer of up to 85,000 candidate clones from a single plate is also elaborated.

The below resources include an eBook which provides context on the use of early productivity screening to guide decision making, and examples of its use in automated monoclonality screening.

eBook Maximizing Efficiency in Cell Line Development

Describing early productivity screening to guide decision making, using a platform which revolutionizes cell line development by integrating single-cell isolation, automated imaging, and early productivity assessment into a unified, high-throughput workflow.

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CellCelector CLD Instrument Flyer

The New CellCelector Cell Line Development (CLD) Platform, where automated imaging, single cell and colony picking, simplify cell line development challenges. With details of media, reagents, workflows and imaging modes which increase sensitivity 16-fold, improving visualization of low-expression targets. All this is a great help in accelerating biopharmaceutical production.

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Case Study, 3D models, iPSC Spheroid Workflows

Developing reliable 3D cell models, such as monoclonal spheroids and hepatic organoids, is complex and resource intensive. This study presents an automated, standardized workflow, which simplifies the generation, monitoring, and analysis of iPSC-derived 3D models. The approach reduces variability, saves time, and supports the development of consistent physiologically relevant models.

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eBook Automated Cell Selection Retrieval CLD Biologics

Automated robotic instruments are revolutionizing scientific research and bringing more productivity and throughput to routine workflows, thus accelerating important discoveries. This eBook highlights how automated, image-based systems, like CellCelector, are simplifying progress in numerous research applications, including rare-cell analysis, cell line development, biologics discovery and stem cell studies.

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